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The only source of CBD oil I personally test and trust

Mike Adams

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One of the reasons Native Hemp Solutions CBD products are frequently out of stock is because the manufacturer is often waiting on me to complete my laboratory quantitation analysis of its cannabinoid components.

Using advanced laboratory instrumentation known as LC-MS-TOF, I measure the concentration of CBD, CBDA and other cannabinoids in their hemp extracts. On top of that, I authenticate the cannabinoid molecules to ensure they’re 100% real (and not counterfeit). In fact, I’m one of the co-developers of a published scientific method for quantitating cannabinoids in hemp extract. Read the original study at this link in the LC/GC journal via (and note my name as one of the co-authors).

Along with my colleagues, we developed a reliable method for measuring the concentrations of 11 cannabinoids all at once, including THC, THCA, CBC, CBD and other cannabinoids. The two that really matter the most in terms of therapeutic applications are CBD and CBDA, by the way. (CBDA is a more complex form of CBD with the addition of a carboxylic acid group. It essentially “degrades” into CBD over time, in the presence of heat. The term “de-carbed” means heating the extract to convert the carboxylic acid forms into simpler cannabinoids.)

Some CBD oil products are wildly inaccurate in their label claims of CBD content

When I first started testing CBD products, I found that some were wildly inaccurate in their label claims. I also found that different labs produced shockingly different results, sometimes disagreeing as much as 50% on their final numbers. Over time, I also learned that accurately quantitating cannabinoids is extremely complex, mostly due to what’s called the “matrix” of other chemical constituents that are often present in hemp extracts.

This same laboratory analysis obstacle is also faced in labs that attempt to test tobacco products, for example, or complex herbal formulas. The more complex the phytochemicals, the harder the laboratory analysis becomes. As a result, we’ve had to develop some extremely clever techniques for achieving accurate quantitation of CBDs in hemp extract products.

And yet, to this day, we find that there are certain other herbs which cause such extreme “ionization suppression” that accurate quantitation is impossible in certain herbal formulas. Some herbs, fascinatingly, seem to cause CBD to vanish, while other herbs appear to form cannabinoids when in the presence of other cannabinoids, which appear to serve as catalysts for chemical reactions that we don’t yet understand. (Your own body, interestingly, generates very small amounts of CBD from your consumption of omega-3 oils.)

Our research continues in this realm, so we’ll hopefully have a more advanced understanding on all this over time. Cannabis is a truly miraculous, complex plant that exhibits properties we have never seen in any other plant matrix. It’s almost like there’s a “molecular code” that has to be untangled… more on that in a future article.

If you’re curious exactly how I quantitate cannabinoids using time-of-flight mass spec instrumentation, here’s a simplified video that gives you a guided tour of how I carry out this science at CWC Labs. Note that this is a vastly simplified public tour video, and what I actually do in the lab is considerably more complex: