Review Supports White Bean Extract Weight Management Potential
Lee Swanson Research Update
According to data in the literature, the alpha-amylase inhibitor called Phase 2® may reduce the rate of carbohydrate absorption, which effectively decreases the glycemic index (GI) of the food.
"Experiments conducted with the Phase 2 alpha-amylase inhibitor indicate that it reduces the rate of absorption of carbohydrates, thereby reducing the GI of foods," wrote Marilyn Barrett from Pharmacognosy Consulting and Jay Udani from Medicus Research LLC in Nutrition Journal.
"The evidence also indicates that Phase 2 promotes weight loss when taken concurrently with meals containing carbohydrates," they added.
According to the review, the weight-loss potential of Phase 2 has been reported in 10 clinical trials, with three studies demonstrating efficacy compared to placebo. Doses used in these studies ranged from 445 mg over four weeks to 3,000 mg over 12 weeks.
In addition, studies have found that the white bean extract may reduce the spike in blood sugar levels after a meal, and that the ingredient can be formulated into foods and beverages "without losing activity or altering the appearance, texture or taste of the food."
"The importance of reducing the GI of foods in weight management and type 2 diabetic control is indicated by an emerging body of evidence," wrote the researchers. "Reducing the post-prandial spikes of glucose and insulin following a high-GI meal may also reduce the risks of developing insulin resistance, which can lead to cardiovascular disease."
Nutrition Journal 10(1):24, 2011
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April 2011