British Prime Minister Theresa May said on Tuesday that authorities were working to establish the details of a blast which killed 19 and injured at least 59 in the northern English city of Manchester, adding that it was being treated as an "appalling terrorist attack."
"We are working to establish the full details of what is being treated by the police as an appalling terrorist attack," she said in a statement.
"All our thoughts are with the victims and the families of those who have been affected."
At least 19 people are confirmed dead and 50 wounded after a reported blast at a concert venue in the northern English city of Manchester.
Reuters reported that two U.S. officials said a suicide bombing was suspected, and Fox News reported that hospital officials said they treated schrapnel-type wounds in the vicitms.
According to the BBC, police discovered what they thought may have been a second explosive device near where the initial attack took place that had not gone off. Police conducted a controlled detonation, and reported it was not an explosive device.
A fleet of ambulances was seen rushing to the Manchester Arena venue after the late Monday incident and police said people should avoid the area. Bomb disposal teams followed soon after.
The deaths followed television footage of people leaving the arena, which had been hosting a concert by the American singer Ariana Grande, in a state of alarm and distress.
One person told the BBC he saw 20 to 30 people lying on the ground.
The first unconfirmed reports of an explosion emerged shortly after 2145 GMT.
The statement issued by Greater Manchester Police that confirmed the deaths did not comment on any possible cause for the apparent explosion.
"Please avoid the area as first responders work tirelessly at the scene," it said, noting that details of a telephone number for concerned families to call would follow.
There had been reports of a loud bang being heard near the end of the concert, causing people to rush for the exits.
Isabel Hodgins, who had been attending the concert, told Sky News: "Everybody was panicking, there was pushing up the stairs.
"The corridor was full, it smelled of burning, there was quite a lot of smoke as we were leaving.
"It's just shocking and we just feel very shaken up. We're just lucky to have gotten away safely."
Several media outlets reported that there had been two explosions from within the 21,000 capacity venue.
Robert Tempkin, 22, from Middlesbrough, told the BBC: "Everyone was screaming and running, there were coats and people's phones on the floor. People just dropped everything.
"Some people were screaming they'd seen blood but other people were saying it was balloons busting or a speaker had been popped.
"There were lots of ambulances. I saw somebody being treated. I couldn't tell what had happened to him."
Suzy Mitchell, whose flat is opposite the venue said: "(I) just heard a huge bang from my bed, came out to the front of my apartment and everyone was running away in big crowds."
Train services to and from Manchester Victoria Station -- located under the Arena -- had been cancelled.
British Transport Police said in a statement: "Officers are at Manchester Arena following reports of an explosion within the foyer area of the stadium at 10.30pm this evening.
"Emergency services are at the scene and we are working to establish more information regarding the explosion and will provide further updates as soon as possible."
The incident caused transport chaos, with traffic jams outside the venue.
"Emergency services are dealing with an incident near Manchester Victoria, resulting in all lines being closed," operator Northern Railway wrote on its website.
Fox News reported that police said they were focusing their investigation on the lobby area of the arena, which is connected to the Manchester train station.
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